Faculty participating in the program hold appointments in either the
Department of Biochemistry and Molecular Biophysics, the Department
of Chemistry, or the Department of Pharmacology and Toxicology.
Investigator
|
Research Interests
|
|
Craig
A. Aspinwall
Chemistry
|
Cellular Function at the Interface of Analytical Chemistry and
Cell Physiology
|
|
Thomas O.
Baldwin
Biochemistry and Molecular Biophysics
|
Protein Folding and Assembly of Multisubunit Complexes; Quorum
Sensing
|
|
Vahe
Bandarian
Biochemistry and Molecular Biophysics
|
Biosynthesis of secondary metabolites; mechanistic enzymology
|
|
Michael
Brown
Chemistry
|
NMR spectroscopy; membrane proteins and lipid bilayers; receptors
and biological signaling; vision
|
Hamish Christie
Chemistry |
Synthetic organic chemistry, with the goal of improving existing methods and discovering new processes including enantioselective reactions |
|
Matthew
Cordes
Biochemistry and Molecular Biophysics
|
Structural Evolution and Conformational Switching in Proteins
|
|
Michael
A. Cusanovich
Biochemistry and Molecular Biophysics
|
Recognition, Protein Dynamics, Protein Stability
|
|
John
H. Enemark
Chemistry
|
Metallo Proteins and their Models
|
|
Indraneel
Ghosh
Chemistry
|
Signal Transduction Pathways, Anti-Cancer Agents and Protein
Based Biosensors
|
|
Robert
J. Gillies
Radiology
|
In vivo Molecular Imaging
|
|
Richard
S. Glass
Chemistry
|
Mechanistic, Synthetic and Structural Chemistry
|
|
Nancy
Horton
Biochemistry and Molecular Biophysics
|
Macromolecular structure and function; X-ray crystallography
|
Christopher Hulme
Chemistry |
Enabling chemistries and platform technologies for the construction of targeted small molecule libraries that span possible applications across multiple target families |
|
Laurence
H. Hurley
Pharmacology and Toxicology
|
Development of antitumor agents
|
|
Victor
J. Hruby
Chemistry
|
Asymmetric Synthesis; Biologically Active Peptides/Mimetics;
Conformation-Activity Relationships
|
|
Elaine
L. Jacobson
Pharmacology and Toxicology
|
DNA Repair/Skin Cancer
|
|
Myron
K. Jacobson
Pharmacology and Toxicology
|
Cell Response to Toxic Chemicals and Radiation
|
Serrine
Lau
Pharmacology and Toxicology |
Environmental causes of disease;
Mechanisms of prostanoid mediated cytoprotection against environmental
chemical-induced toxicity; Development of mass spectrometric-based
proteomics approaches to study chemical-induced protein modifications
which impact on specific cellular functions. |
|
John
W. Little
Biochemistry and Molecular Biophysics
|
Biochemical, Genetic and Systems Analysis of Gene Regulation
|
|
Eugene
A. Mash, Jr.
Chemistry
|
Organic Synthesis; Medicinal Chemistry; Chemical Toxicology
|
|
Megan
M. McEvoy
Biochemistry and Molecular Biophysics
|
Structure/Function of Protein Complexes
|
|
Katrina
M. Miranda
Chemistry
|
Chemical Biology of Nitrogen Oxides; New Detection
Techniques and Donors of Nitrogen Oxides; Drug
Development
|
Osamu Miyashita
Biochemistry and Molecular Biophysics |
Theoretical and Computational Biophysics, Molecular Dynamics
Simulations, Protein Electron Transfer, Protein Allostery |
|
William
R. Montfort
Biochemistry and Molecular Biophysics
|
Protein structure, function and dynamics; X-ray crystallography
|
Bogdan
Olenyuk
Chemistry |
Recognition of cell surface receptors with
synthetic macromolecules; Chemical control of cell adhesion and
migration; Design of small molecules for control of protein levels
via targeted degradation |
|
Robin
L. Polt
Chemistry
|
Cell-surface Carbohydrates
|
|
S.
Scott Saavedra
Chemistry
|
Interfacial Optics, Biofilms, Biosensors
|
|
William M. Schaffer
Ecology and Evolutionary Biology
|
Nonlinear Biological Dynamics
|
Catharine L. Smith
Pharmacology and Toxicology |
Epigenetic mechanisms of gene expression,
their regulation through signaling pathways and modulation by anti-cancer drugs |
Florence Tama
Biochemistry and Molecular Biophysics |
Computational Structural Biology, Function and Dynamics of
Macromolecular Assemblies, Multi-Scale Modeling, Methods Development
to Interpret Experimental Data |
|
Gordon
Tollin (emeritus)
Biochemistry and Molecular Biophysics
|
Mechanisms of Biological Electron Transfer; Photochemical Energy
Conversion; Signal Transduction
|
|
Elizabeth
Vierling
Biochemistry and Molecular Biophysics
|
Function of Molecular Chaperones
|
|
Koen
Visscher
Physics
|
Molecular Motors
|
|
Francis
Ann Walker
Chemistry
|
Structure, Function and Spectroscopy of Heme Proteins
|
|
Mary
J. Wirth
Chemistry
|
Design of new separations for biomolecules, and study of the
adsorption of biomolecules to surfaces.
|
Georg Wondrak
Pharmacology and Toxicology |
Molecular pathways of skin photocarcinogenesis
that involve cellular photooxidative and carbonyl stress;
Developing
chemical
reagents into potent drugs that target reactive chemical
intermediates |
|
Vicki
H. Wysocki
Chemistry
|
Peptide and Protein Characterization by Tandem Mass Spectrometry
|
|
Danzhou
Yang
Pharmacology and Toxicology
|
Structure and Function of DNA and DNA-interacting Proteins as Anticancer Drug Targets; High-field NMR spectroscopy |
Donna Zhang
Pharmacology and Toxicology |
The Nrf2/Keap1 signaling pathway that is activated by oxidative stress and chemopreventive compounds; Regulation of gene expression by the ubiquitination and proteasomal degradation pathway |
