May 10, 1999
The exam 4 questions and key
have been posted. The TAs will be done
grading by Tuesday and grades will be available by Wednesday.
I will
post them on the gradebook page, and also put a hard copy outside
of the
Biochemistry office (BSW 357). Your graded exams can be picked
up
in BSW 364 anytime after noon on Wednesday.
Have a nice summer and remember to use
sun screen!
May 6, 1999
Exam 4 is at 2 pm Friday May 7 in the same room (BSW 301).
You can use the scheduled 2 hours if you need it.
The TAs will grade the exams by Tuesday and you can pick them
up
in BSW 364 beginning Wednesday morning. Your final grade in the
course will be posted on the website and also outside of BSW 364
by the
end of next week (May 14). Check this announcement page for details
later.
May 4, 1999
The completed Exam 4 study question set
is now posted along with
an answer key.
May 3, 1999
I posted the key to the partial
list of study questions. I hope to be able
to add a few more questions tonight covering the last two lectures.
April 30, 1999
A partial list of exam 4 review questions
has been posted. Questions
relating to lectures 40 and 41 will be posted on Monday along
with an
answer key to all the questions.
April 29, 1999
The material on steroid hormone action originally included in
Lecture 37 has been moved to Lecture 40 (Hormone Action).
A new lecture 37 page has been
posted. What does this all mean?
You will be responsible for the
material discussed in class entitled
"Glucocorticoid regulation of PEPCK
expression" .
April 26, 1999
Exam 4 review session is scheduled for Wednesday,
May 5
from 5:30 - 7:00 pm in BSW 301 (lecture room). Bring your
questions and misconceptions. I will get a set of review questions
written and posted by Friday of this week, with answers posted
on Monday.
April 21, 1999
I made one correction in the lecture
35 notes. The revision
is in the numer of ATP required for citrate shuttle, the net
requirement is 2 ATP ---> 2 ADP + 2 Pi as now shown.
April 20, 1999
A new figure has been added to lecture 34 to more clearly
show the products from palmitate oxidation (RLM
34.2).
April 19, 1999
The lecture notes for Fatty Acids Part 1 (lecture
34)
have been corrected to show that palmitate is oxidized
in a reaction using 7 NAD
---> 7 NADH (sorry about that!)
April 18, 1999
The class distribution of total points
for all three exams
has been posted. Provisional letter grades are shown as
a guide, these are NOT actual grades, but rather estimates
of how the grades MAY end up.
April 17, 1999
Distribution of Exam 3 scores
are posted.
April 16, 1999
Two summary figures have been added to lecture
33. One
is what happens when you see a snake,
and the other shows
what happens when you eat a cake.
They are referred to as
RLM 33.1 and RLM 33.2 in the notes. Also a revision was
made in the section on hormonal regulation - now emphasizing
the regulatory role of phosphorylation/dephosphorylation.
April 15, 1999
The answer key for exam 3 has been modified to include
credit for "decrease" in rate of ATP synthesis in the
presence of DNP
for question 9. I still think "no change" is the BEST answer, but I
am willing to admit that the question was somewhat ambiguous.
April 13, 1999
Exam 3 with answers
has been posted. Note that everyone
who wrote their name on the exam got a bonus
of 3 pts.,
(I mistakenly only had 97 pts total on the exam - oops!).
April 12, 1999
This is not on exam 3, but
I wanted to correct a mistatement
I made in class on Friday. The chlorplast
stroma IS
functionally
similar to the mitochondrial matrix. Both of these
compartments
contain the F1 portion of ATP synthase and low [H+] concentration.
The thykaloid space and the intermitochondrial membrane space
are
functionally similar; they both have high [H+] and protons flow
through the F0 component of ATP synthase. The lecture notes
correctly state that the stroma is similar to the matrix.
April 6, 1999
Since a number of students asked me about it, and I didn't
have time to go over it in class, I posted the answer to the
question, "Where does the 2.5 ATP per
1 NADH come from?"
I call this Difficult Concept 3 -
RLM 29.3 and linked it to the
Lecture 29 notes.
- also note that two more questions were added to the review
for exam 3 (20a and 20b). These were given in class during
lecture 25 (fructose metabolism), I just forgot to include them.
April 5, 1999
I drew a diagram of the glycerol phosphate shuttle to better
illustrate what is shown in the text figure 21.30. My new
drawing is RLM 29.1 and is linked to lecture 29.
April 3, 1999
Review questions for exam 3 have been posted under Review
Materials. The answer key for these questions will be posted
Thursday, April 8. It is strongly recommended
that you try
to work through as many of these questions as you can prior
to the key being posted. I will be happy to discuss any of these
questions during office hours and at the review
session on Wednesday.
April 2, 1999
BSW 301 has been reserved from 5 - 7 pm Wednesday, April 7,
for Exam 3 review session. Bring your questions and misconceptions.
Note: There was an error (not mine!) on the metabolic illustration
of
mitochondrial reactions I pulled from the WWW - RLM28.1.
It has
now been corrected to show 3 NADH
are produced (not NADPH).
March 31, 1999
We will finish the last part of the CAC lecture on Friday due
to fire alarm.
There is a correction on figure RLM 25.4, the text should state
that pyruvate
kinase is inactivated by phosphorylation
(not dephosphorylation), see fig. 19.9
in Stryer. I corrected this on the web page so the printout of
RLM 25.4 is correct.
March 30, 1999
A short description of the enzyme aconitase has been added to
lecture 27.
Study questions for exam 3 will be posted on the web before Monday,
April 5.
March 29, 1999
The CAC chemical structure diagrams RLM 26.1 & RLM 27.1 have
been corrected.
March 28, 1999
It would be helpful for you to print the CAC diagram (RLM
26.1) and bring
it to lecture on Monday. Likewise, you will need RLM 27.1 for
the lecture on
Wednesday in order to "follow the bouncing carbon."
March 26, 1999
The protein structures and summary of enzyme properties shown
in class
for hexokinase, phosphofructokinase, triosephosphate isomerase,
and pyruvate
kinase, have been made into JPEG files and linked to Lecture 25
notes (see new).
March 24, 1999
Lecture notes for lectures 24 and 25 contain links to biochemistry
web sites of
tutorials for studying glycolysis. I will use these sites in class
and you should
at least print out the Glycolytic Pathway diagram.
It will also be very helpful to view the molecular structures
of key glycolytic
enzymes using the Netscape Plug-in called Chime. This is a freeware
application program that you can obtain from the Get
Chime help page.
Please ask us for help if you have trouble getting this to run
on your
computer. Note that you can also view these structures on the
computers in the
Biology Learning Center (BLC) and Science Library if you don't
have
access to the Internet from home.
March 21, 1999:
Please try to bring your textbook to class to follow along with
the lectures,
Internet posting of figures from Stryer will no longer be done.
Sorry.
March 12, 1999:
The Grade Distrubution graph for Exam 2 is posted under gradebook.
March 10, 1999:
- No Class on Friday - enjoy your Spring Break!
- Exam 2 will be available for pick-up from 3:00 - 3:15 pm
on Friday for
those students who can't wait for the results. David and Unsal
will be in
BSW 301 for 15 minutes only. The rest of the exams will be distributed
Monday, March 22.
- Lecture 22 notes are being updated today, the complete set
of figures and
text for lecture 22 will be done by Thursday, if not earlier.
Future
lectures will be posted ahead of time. The figures are JPEG files,
and
therefore, the resolution is not that great for printing, but
good enough
to follow along in lecture and they look fine in a web browser.
Let Dr.
Miesfeld know by e-mail if you have any problems printing the
lecture notes.
March 3, 1999:
A sample test, with answers, is posted under review
materials
February 15, 1999:
The Grade Distrubution graph for Exam 1 is posted under gradebook.
February 9, 1999:
The key for exam one is posted under exams.
January 25, 1999:
SALT students: A room has been reserved for taking exams according
to the
SALT Center policies. If you are a participant in this program,
and Dr.
Miesfeld has been notified by Diedre Rapp at the SALT Center,
you should
report to the following rooms to take your Bioc 460 exams.
If you have any
questions, please contact Dr. Miesfeld.
Exam 1 Mon Feb 8
3pm - 5pm BSW 510
Exam 2 Mon Mar 8
3pm - 5pm BSW 364
Exam 3 Mon Apr 12 3pm
- 5pm BSW 510
Exam 4 Fri
May 7 2pm - 4pm BSW 510
January 21, 1999:
The text of Dr. Cusanovich's overhead transparencies for lectures
1-5 are posted under "lectures".
The figure numbers in the lecture notes refer to the Stryer Biochemistry
textbook.
Welcome to Spring Semester BIOC 460!
Please read the course information that has been posted and check this Spring BIOC 460 Announcement page regularly to find out about study guides and other important notices.
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Department of Biochemistry http://www.biochem.arizona.edu/classes/bioc460/spring/html/announce.html
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