mystery protein

 

 

 

 

 

Lecture Materials - Summer 2008

To read PDF versions of the lecture notes, you need to get your free copy of Acrobat Reader. Click on the Adobe icon and follow the instructions. If you have questions or problems, contact Dr. Ziegler by e-mail at zieglerm@u.arizona .edu. The Bioc 460 lecture notes contain copyrighted textbook materials and are password protected.

Remember to refresh or reload your browser window to update the listing below. If you are using AOL and having troubling refreshing your browser window, click here for some help.

Updated on 4/4/08

Date

Lecture

Topic

Lecture Notes
(PDF-2: 2 slides/page)
(PDF-6: 6 slides/page)

Berg et al., 6th ed. Chapter: pages

Berg et al., 5th ed. Chapters: pages

Instructor

M - May 19

1

Introduction, Properties of Water

Introduction
[PDF-2] [PDF-6]
logarithms review
Gen Chem Review [PDF]

1

1;
2: 73-74

Ziegler

T - May 20

2

Bioenergetics
-------------------------------
Amino Acids
(excellent additional AA website)
-------------------------------
Gen Chem Review after class (room TBA)

Bioenergetics
[PDF-2] [PDF-6]
bioenergetics sample problems [PDF]
----------------
Amino acids
[PDF-2] [PDF-6]

1: 11-14;
8: 208-210;
---------------
2: 25-34

1: 11-14;
8: 193-194;
--------------
3: 41-51

Ziegler

W - May 21

3

Amino Acids
-------------------------------
Peptides & Protein Primary Structure
-------------------------------
Gen Chem Review after class (room TBA)


Amino acids
[PDF-2] [PDF-6]
----------------
Peptides
[PDF-2] [PDF-6]
Peptide/pH Practice Problems [PDF]

2: 34-37

3: 51-56

Ziegler

Th - May 22

4

Peptides & Protein Primary Structure
-------------------------------

Protein Secondary Structure

Peptides
[PDF-2] [PDF-6]
----------------
Secondary Struct.
 [PDF-2][PDF-6]

2: 37-45

3: 56-61

Ziegler

F - May 23

5

Protein Secondary Structure
-------------------------------
Proteins, Tertiary & Quaternary Structure

Secondary Struct.
 [PDF-2][PDF-6]
----------------
Tert/Quat Struct.
[PDF-2] [PDF-6]

2: 44-53;
61-62

3: 61-64

Ziegler

M - May 26

 

Memorial Day (HOLIDAY)

       

T - May 27

6

Proteins: Folding
-------------------------------
Protein Function: Ligand Binding and Allostery (Myoglobin and Hemoglobin);

Protein Folding
 [PDF-2] [PDF-6]
----------------
Mb and Hb
 [PDF-2] [PDF-6]

2: 53-60

 

 

7: 183-199

3: 64-72

3: 61-62: 10: 268-274

Ziegler

W - May 28

7

Protein Function: Ligand Binding and Allostery (Myoglobin and Hemoglobin); Quiz 1

(same notes as above)

 

 

Ziegler

Th - May 29

8

Enzymes: Introduction

Enz-Introduction
[PDF-2] [PDF-6]
enzyme introduction sample problems [PDF]

8: 205-216

8: 189-200

Ziegler

F - May 30

9

Enzymes: Kinetics

Enz-Kinetics
[PDF-2] [PDF-6]

8: 216-225

8: 200-208, 221-222

Ziegler

M - June 2

10

Enzymes: Inhibition  

Enz-Inhibition
[PDF-2] [PDF-6]

8: 225-236

8: 209-221

Ziegler

T - June 3

11

Enzymes: Catalytic Strategies
(help session after class, CHEM 111)

Enz-Cat Mechs
[PDF-2] [PDF-6]

9: 241-254

9: 227-239

Ziegler

W - June 4

 

EXAM 1

 

 

 

Th - June 5

12

Regulatory Strategies: Allosteric Regulation; Isozymes

Regulation-Allost.
[PDF-2] [PDF-6]

10: 275-288

10: 261-269, 274-280

Hazzard

F - June 6

13

Regulatory Strategies: Reversible Covalent Modification, Regulatory Proteins, Proteolytic Cleavage

Regulation-Covalent, Reg. Proteins, Zymogen Activation
[PDF-2] [PDF-6]

14: 389-391;
10: 288-299

15: 408-411;
10: 280-291

Hazzard

M - June 9

14

Membranes: Lipids

Membranes-Lipids
[PDF-2] [PDF-6]

12: 326-335

12: 319-329

Hazzard

T - June 10

15

Membranes: Proteins

Membranes-Proteins
[PDF-2] [PDF-6]

12: 336-348

12: 329-342

Hazzard

W - June 11

16

Membranes: Transport 1

Membranes-Transport
[PDF-2] [PDF-6]

13: 351-376

13: 345-365

Hazzard

Th - June 12

17

Membranes: Transport 2 or catch-up ; Quiz 2

(same notes as Lecture 16)

13: 351-376

13: 345-365

Hazzard

F - June 13

18

Metabolic Concepts

[PDF]

Power-point

15: 410-420, 428-429;
27: 770-774

14: 374-383, 390-391;
30: 854-858

Tischler

M - June 16

19

G-Protein Signaling

[PDF]

Power-point

14: 382-391, 399-402;
10: 284-288

15: 399-407, 410-411, 418-419 ;
10: 278-279

Tischler

T - June 17

20

Insulin Signaling

[PDF]

Power-point

14: 391-395

15: 414-416

Tischler

W - June 18

21

Glycolysis/Gluconeogenesis 1

[PDF]

Power-point

16: 434-452

16: 428-443

Tischler

Th - June 19

22

Glycolysis/Gluconeogenesis 2

[PDF]

Power-point

16: 452-470

16: 443-460

Tischler

F - June 20

23

PDH, Citrate Cycle (on Exam 3)
(help session after class, CHEM 111)

[PDF]

Power-point

17: 475-493; 18: 503-504

17: 466-482; 18: 492-493

Tischler

M - June 23

 

EXAM 2

 

 

 

 

T - June 24

24

Redox; Respiratory Chain

[PDF]

Power-point

18: 502-517

18: 492-506

Tischler

W - June 25

25

Oxidative Phosphorylation

[PDF]

Power-point

18: 520-524, 527-534

18: 507-511, 514-521

Tischler

Th - June 26

26

Pentose Pathway and Antioxidants

[PDF]

Power-point

18: 517-519; 20: 577-587; 24: 701

18: 506-507; 20: 563-572; 24: 686

Tischler

F - June 27

27

Glycogen - Allosteric Control

[PDF]

Power-point

21: 592-601, 604-607, 611-612

21: 577-586, 589-591, 595-596

Tischler

M - June 30

28

Glycogen - Hormonal Control

[PDF]

Power-point

21: 598-604, 607-611

21: 586-588, 592-595

Tischler

T - July 1

29

Cholesterol; Quiz 3

[PDF]

Power-point

26: 739-743, 748-755

26: 722-727, 731-738

Tischler

W - July 2

30

Lipid Transport

[PDF]

Power-point

22: 619-620; 26: 745-748

22: 603-604; 26: 727-731

Tischler

Th - July 3

31

Lipolysis; β-Oxidation; Ketones; Lipogenesis

[PDF]

Power-point

22: 619-644

22: 603-628

Tischler

F - July 4

 

HOLIDAY

        

M - July 7

32

Lipid Regulation

[PDF]

Power-point

22: 621-622, 640-642; 26: 742-743

22: 605-606, 624-626; 26: 726-727

Tischler

T - July 8

33

Ammonia Metabolism, Urea Cycle

[PDF]

Power-point

23: 656-674

23: 639-657

Tischler

W - July 9

34

Nitrogen Metabolism
(help session after class, CHEM 111)

[PDF]

Power-point

24: 685-693, 702-705  

24: 670-678, 687-689

 Tischler

Th - July 10

 

EXAM 3

 

 

 

  
zieglerm@u.arizona .edu
Department of Biochemistry
The University of Arizona
Copyright (©) 2008
All rights reserved.