|
Lecture
|
Date
|
Class
|
Lecturer
|
Topic
|
Chapter (Lehninger Principles of
Biochemistry, 4th ed.)
|
|
1
|
Aug. 20 (M)
|
Lecture
|
Ziegler/McEvoy/Baldwin
|
Introduction
|
1 (pp. 3-21)
|
|
|
Aug. 21 (Tu), 5:00-6:15 pm;
Aug. 22 (W), 4:00-5:15 pm
|
general chem review (duplicate
sessions -- just attend one time)
|
Faculty
|
Chemical Equilibrium, pH, pKa, etc.
ROOMS:
Tues., BioW 301;
Wed., CESL 103 (right after class)
|
1 (p. 26)
2 (pp. 60-69)
|
|
2
|
Aug. 22 (W)
|
Lecture
|
Ziegler
|
Water Properties/Noncovalent Interactions
|
2
|
|
|
Aug. 22-23 (W-Th)
|
Discussion (Prob. Set 1)
|
|
Water/Acid-Base
|
|
|
3
|
Aug. 24 (F)
|
Lecture
|
Ziegler
|
Bioenergetics
|
1 (pp.21-28); 13 (pp. 481-507)
|
|
4
|
Aug. 27 (M)
|
Lecture
P.S. 1 due
|
Ziegler
|
Bioenergetics
|
13 (pp. 481-507)
|
|
5
|
Aug. 29 (W)
|
Lecture
|
Ziegler
|
Bioenergetics
|
13 (pp. 481-507)
|
|
|
Aug. 29-30 (W-Th)
|
Discussion (Prob. Set 2)
|
|
Bioenergetics
|
|
|
6
|
Aug. 31 (F)
|
Lecture
P.S. 2 due
|
Baldwin
|
Amino Acids
|
3 (pp. 75-89)
|
|
|
Sept. 3 (M)
|
NO CLASS
|
|
LABOR DAY |
|
|
7
|
Sept. 5 (W)
|
Lecture
|
Baldwin
|
Amino Acids/Peptides
|
3; 4 (pp. 116-144) |
|
|
Sept. 5-6 (W-Th)
|
Discussion (Prob. Set 3)
|
|
Amino Acids/Peptides
|
|
|
8
|
Sept. 7 (F)
|
Lecture, 10-min quiz
P.S. 3 due
|
McEvoy
|
Protein Secondary Structure
|
4 (pp. 116-144) |
|
9
|
Sept. 10 (M)
|
Lecture
|
McEvoy
|
Protein Tertiary Structure
|
4 (pp. 116-144) |
|
10
|
Sept. 12 (W)
|
Lecture
|
McEvoy
|
Protein Tertiary Structure
|
4 (pp. 116-144) |
|
|
Sept. 12-13 (W-Th)
|
Discussion (help session)
|
|
Review
|
|
|
11
|
Sept. 14 (F)
|
Lecture
|
Baldwin
|
Protein Quaternary Structure
|
4 (pp. 144-151) |
|
|
Sept. 17 (M)
|
EXAM 1
|
|
|
|
|
12
|
Sept. 19 (W)
|
Lecture
|
Baldwin
|
Protein Folding and Stability |
4 (pp. 144-151) |
|
|
Sept. 19-20 (W-Th)
|
Discussion (Prob. Set 4)
|
|
Protein Structure (online, in BMB computer lab, Room 243
BSW; open 8 am-3:50 pm)
|
|
|
13
|
Sept. 21 (F)
|
Lecture
P.S. 4 due
|
Dr. Matt Cordes
(guest lecture)
|
Molecular Evolution of Proteins
|
3 (pp. 106-110); 4 (pp. 141-144)
|
|
14
|
Sept. 24 (M)
|
Lecture
|
Ziegler |
Protein Function - Myoglobin |
5 |
|
15
|
Sept. 26 (W)
|
Lecture
|
Ziegler |
Hemoglobin |
5 |
|
|
Sept. 26-27 (W-Th)
|
Discussion (Prob. Set 5)
|
|
Protein Structure & Stability, Ligand Binding
|
|
|
16
|
Sept. 28 (F)
|
Lecture
P.S. 5 due
|
Ziegler
|
Hemoglobin
|
5
|
|
17
|
Oct. 1 (M)
|
Lecture
|
Ziegler
|
Hemoglobin
|
5
|
|
18
|
Oct. 3 (W)
|
Lecture
|
McEvoy
|
Contractile Proteins
|
5
|
|
|
Oct. 3-4 (W-Th)
|
Discussion (Prob. Set 6)
|
|
Hemoglobin/Contractile Proteins
|
|
|
19
|
Oct. 5 (F)
|
Lecture, 10-min quiz
P.S. 6 due
|
Baldwin |
Enzymes: Introduction
|
6 (pp. 191-209) |
|
20
|
Oct. 8 (M)
|
Lecture
|
Baldwin |
Enzyme Kinetics |
6 (pp. 191-209) |
|
21
|
Oct. 10 (W)
|
Lecture
|
Baldwin |
Enzymes: Bisubstrate reactions |
6 (pp. 191-209) |
|
|
Oct. 10-11 (W-Th)
|
Discussion (help session)
|
|
Review
|
|
|
22
|
Oct. 12 (F)
|
Lecture
|
Baldwin |
Enzymes: Inhibition
|
6 (pp. 209-225) |
|
|
Oct. 15 (M)
|
EXAM 2
|
|
|
|
|
23
|
Oct. 17 (W)
|
Lecture |
Baldwin |
Enzymes: Inhibition, Mechanisms |
6 (pp. 209-225) |
|
|
Oct. 17-18 (W-Th)
|
Discussion (Prob. Set 7)
|
|
Enzymes
|
|
|
|
Oct. 19 (F)
|
NO CLASS |
|
Family Weekend, Honors Convocations (3 pm) |
|
|
24
|
Oct. 22 (M)
|
Lecture
P.S. 7 due
|
Baldwin |
Enzymes: Chemical Mechanisms |
6 (pp. 209-225) |
|
25
|
Oct. 24 (W)
|
Lecture
|
Baldwin |
Enzymes: Chemical Mechanisms |
6 (pp. 209-225) |
|
|
Oct. 24-25 (W-Th)
|
Discussion (Prob. Set 8)
|
|
Enzyme Mechanisms
|
|
|
26
|
Oct. 26 (F)
|
Lecture
P.S. 8 due
|
Baldwin |
Enzymes: Chemical Mechanisms |
6 (pp. 209-225) |
|
27
|
Oct. 29 (M)
|
Lecture
|
Baldwin |
Enzymes: Chemical Mechanisms |
6 (pp. 209-225) |
|
28
|
Oct. 31 (W)
|
Lecture
|
Ziegler |
Enzymes: Regulation |
6 (pp. 225-233) |
|
|
Oct. 31-Nov. 1 (Th)
|
Discussion (Prob. Set 9)
|
|
Enzyme Mechanisms, Regulation
|
|
|
29
|
Nov. 2 (F)
|
Lecture, 10-min. quiz
P.S. 9 due
|
Ziegler |
Enzymes: Regulation |
6 (pp. 225-233) |
|
30
|
Nov. 5 (M)
|
Lecture
|
Ziegler |
Enzymes: Regulation |
6 (pp. 225-233) |
|
31
|
Nov. 7 (W)
|
Lecture
|
Ziegler |
Carbohydrates and Glycobiology |
7 |
|
|
Nov. 7-8 (W-Th)
|
Discussion (help session)
|
|
review |
|
|
32
|
Nov. 9 (F)
|
Lecture |
Ziegler |
Carbohydrates/Glycobiology/Lipids |
7; 10 |
|
|
Nov. 12 (M)
|
NO CLASS
|
|
VETERANS' DAY
|
|
|
|
Nov. 14 (W)
|
EXAM 3 |
|
|
|
|
|
Nov. 14-15 (W-Th)
|
Discussion (Prob. Set 10)
|
|
Enzyme Regulation/Carbohydrates/Lipids
|
|
|
33
|
Nov. 16 (F)
|
Lecture
P.S. 10 due
|
Ziegler/McEvoy
|
Lipids/Membranes
|
10; 11
|
|
34
|
Nov. 19 (M)
|
Lecture
|
McEvoy
|
Membrane Proteins
|
11
|
|
|
Nov. 21 (W)
|
NO CLASS
|
|
|
|
|
|
Nov. 22/23 (Th-F)
|
NO CLASS
|
|
THANKSGIVING
|
|
|
35
|
Nov. 26 (M)
|
Lecture
|
McEvoy
|
Membranes: Transport
|
11
|
|
36
|
Nov. 28 (W)
|
Lecture
|
McEvoy
|
Membranes: Transport
|
11
|
|
|
Nov. 28-29 (W-Th)
|
Discussion (Prob. Set 11)
|
|
Transport/Nucleic Acids
|
|
|
37
|
Nov. 30 (F)
|
Lecture, 10-min quiz
P.S. 11 due
|
McEvoy
|
Nucleic Acids
|
8
|
|
38
|
Dec. 3 (M)
|
Lecture
|
McEvoy
|
Nucleic Acids
|
8
|
|
39
|
Dec. 5 (W)
|
Lecture
|
McEvoy
|
Nucleic Acids
|
8
|
|
|
Dec. 6 (Th)
("Dead Day")
|
Review/help session
|
Faculty
|
Help Session 1:30-3:00 pm (reg. classroom, CESL 103)
|
|
|
|
Dec. 12 (W)
|
FINAL EXAM
|
CESL 103
2:00-4:00PM
|
NOTE START TIME!
Approx 50% last part of course, and 50% material from first three parts of course
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