Free Energy Problem #1

1.  If the equilibrium concentrations of ATP = 1x10^-7 M, ADP = 0.165 M and P_i = 0.1 M, what is the equilibrium constant and DG^o' for the hydrolysis of ATP at 37^oC?

• Use the data to calculate K_eq
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• K_eq = 1.65 x 10⁵ M (note units!)
  
  
• Use the value of  K_eq to calculate DG^o'
  • DG^o' = -RTln K_eq
  • DG^o'= - 8.314x10^-3kJ/K•mol x 310K x ln (1.65 x 10⁵)
  • DG^o' = -31 kJ/mol.