Free Energy Calculations - Step-by-step Answers

 

  1. If the equilibrium concentrations of ATP = 1x10-7 M, ADP = 0.165 M and Pi = 0.1 M, what is the equilibrium constant and DGo' for the hydrolysis of ATP at 37oC? (step-by step answer).
  2. In a typical cell at 37oC the concentration of ATP = 8 x 10-3 M, ADP = 1 x 10-3 M, and Pi = 8 x 10-3 M. What is the actual free energy change (DG') for ATP hydrolysis under these conditions? ( step-by step answer).

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Biochemistry 462a
http://www.biochem.arizona.edu/classes/bioc462/462a/462a.html
Department of Biochemistry and Molecular Biophysics
The University of Arizona
zieglerm@u.arizona.edu 
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Last revised fall 2002