Collagen

Introduction - This script shows the structure of collagen. Scroll down until the text corresponding to the view is visible (Based on 1CAG.pdb, W. Kabach et al. Nature 347 37 (1990)).




A classic collagen triple helix is shown here. The three helices are red, yellow and green.




A special amino acid sequence makes the tight collagen triple helix particularly stable. Every third amino acid is a glycine, and many of the remaining amino acids are proline or hydroxyproline.


Notice how the glycine forms a tiny elbow packed inside the helix, while the proline and hydroxyproline smoothly bend the chain back around the helix.