Human P-glycoprotein

 Webpage Text and Design: Mandy Redig (aredig@u.arizona.edu)

Honors Biochemistry 462b University of Arizona Spring 2001

To learn more about this amazing protein, pictured below, please follow the links on the left-hand side of the page.

Introduction

Structure and Function

Pgp Nucleotide Binding

Pgp Nucleotide Hydrolysis

Substrates and the Catalytic Cycle

Substrate Recogntion

Membrane Interactions

Signal Transduction Connections

Apoptosis Connections

Ion Channel Activation

Summary Points

Conclusion

References

last updated 5/9/01