Conclusion
Auxin has been studied for over 100 years and is extremely well characterized physiologically. There is probably more than one pathway for auxin biosynthesis. This redundancy makes it extremely difficult to isolate auxin biosynthesis mutants as a result of overlapping functions between the different pathways.
The discovery of a YUCCA and evidence that it functions as a FMO suggests that auxin biosynthesis occurs through this previously unlikely pathway. YUCCA is the first FMO identified in plants. Mammalian FMOs have been extensively characterized biochemically, but little is understood about their physiological roles. The discovery of YUCCA suggests that FMOs could also be involved in mammalian tryptophan metabolism (Zhoa et al 2001).
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