References and Further Reading
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Further Reading and Sources

All the sources cited are listed below along with some other helpful websites for the curious.


Sources

Begun DJ. Origin and Evolution of a New Gene Descended From alcohol dehydrogenase in Drosophila, Genetics: 145 (1997) 375-382.

Boffetta P, Hashibe M. Alcohol and Cancer, Lancet Oncol: 7 (2006) 149–56.

Bradbury MW. Lipid Metabolism and Liver Inflammation. I. Hepatic fatty acid uptake: possible role in steatosis, AJP – GI 290:194-198, 2006.

California Environmental Protection Agency: Air Resources Board. “Acetaldehyde as a Toxic Air Contaminant.” Prepared by the Staffs of the Air Resources Board and Office of Environmental Health Hazard Assessment. November 1993.

Chudler, Eric H. Ph.D. “Neuroscience for Kids: Alcohol.” Last modified April 22, 2006.

Dunlap, Michaele P., Psy.D, “Biological Impacts Of Alcohol Use: An Overview.”

Kono H, Arteel GE, Rusyn I, Sies H, and Thurman RG. Ebselen prevents early alcohol-induced liver injury in rats, Free Radic. Biol. Med. 30 (2001) 403–411.

Leeds Dental Institute. Ethanol metabolism

Luczaj W and Skrzydlewska E. Antioxidant properties of black tea in alcohol intoxication, Food Chem. Toxicol. 42 (2004) 2045–2051.

Mercurio SD, Combs GF Jr. Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick, Biochem Pharmacol: 35(24) (1986) 4505-9.

Nelson, David and Michael Cox. Lehninger: Principles of Biochemistry. Fourth Edition. W.H. Freeman and Company. New York: 2005. Page 540 ethanol metabolism

Ostrowska J, Luczaj W, Kasacka I. Rozanski A, Skrzydlewska E. Green tea protects against ethanol-induced lipid peroxidation in rat organs, Alcohol 32 (2004) 25–32.

Ozak M, Nakamura M, Teraoka S, and Ota K. Ebselen a novel anti-oxidant compound, protects the rat liver from ischemiareperfusion injury, Transplant Int. 10 (1997) 96–102.

Pivetta LA, Dafre AL, Zeni G, Rocha JBT, Farina M. Acetaldehyde does not inhibit glutathione peroxidase and glutathione reductase from mouse liver in vitro. Chem Biol Interact: 159(3) (2006) 196-204.

Pushpakiran G, Mahalakshmi K, Anuradha CV. Protective effects of taurine on glutathione and glutathione-dependent enzymes in ethanol-fed rats, Pharmazie 59 (2004) 869–872.

Salaspuro VJ, Hietala JM, Marvola ML and Salaspuro MP. Eliminating Carcinogenic Acetaldehyde By Cysteine From Saliva During Smoking, Cancer Epidemiology Biomarkers & Prevention Vol. 15 (2006) 146-149.

South, James A., M.A. “Acetaldehyde: A Common and Potent Neurotoxin.” Vitamin Research Products.

US Environmental Protection Agency. “Technology Transfer Network Air Toxics Website: Acetaldehyde.” Last updated on Wednesday, March 8th, 2006.

Wikipedia Free Encyclopedia. “Alcohol Dehydrogenase.” Last modified 16:06, 22 April 2006.

Zhao R, Masayasu H, and Holmgren A. Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant, Proceedings of the National Academy of Sciences of the United States of America: Vol 99 Number 13 (2002) 8579-8584.

Figure Sources

Figure 1: Ethanol Metabolism to Acetaldehyde by Acetaldehyde Dehydrogenase

Figure 2: An Ethanol Molecule

Figure 3: The Enzyme Alcohol Dehydrogenase

Figure 4: Acetaldehyde

Figure 5a and b: Fatty Liver and Healthy Liver

Figure 6: Cancer Cells

Figure 7a: Liver

Figure 7b: Liver Diagram

Figure 8: Glucose as an Important Biochemical Energy Source

Figure 9: Tylenol as Potentially Harmful to the Liver

Figure 10: Glutathione Peroxidase

Figure 11: Ebselen

Figure 12: Glutathione Reductase

Figure 13: A Mouse: the Experimentee is a cropped version of the image at this website

Figure 14: Pre-Incubation Results is a graph based on a figure in Pivetta et al's paper

Figure 15: Liver Cell Cytosol

Acetaldehyde Structure at the top left corner of the page has been adapted from this website

Background image has been adapted from this website

 

 

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Spring 2006. Jennifer Lowe Bioc 462b Honors. University of Arizona. Created under the guidance of Dr. Bourque.
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