Discovery
The determination
of the first eukaryotic PII protein structure has resulted in the
discovery of novel plant-specific highly conserved features [1].
The investigators
utilized well-developed molecular experimental techniques to express
and investigate the A. thaliana PII protein in order to obtain
an excellently resolved structure at 1.9 angstroms.
The features
unique to plants in the protein-protein interaction domains, surface
A and surface B, lead to speculation for novel functions and specificities
within higher organisms that are absent in prokaryotes.
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