Catch up on Resonance Assignment Part II

no new reading

Problem set 1 due

Solving NMR Structures, Part I:
Experimentally Derived Structural Restraints

None

Solving NMR Structures, Part II:
Calculating and Evaluating Structures

lecture slides (PPT file)
Teng, Chapter 7

Computer lab 2 assignment due

(from Feb 12)

Solving NMR structures Part II continued,

Intro to Calmodulin system

Computer lab 3

Examining the apo-Calmodulin ensemble with MOLMOL

lab instructions handout in class;

bring Kuboniwa article along!

meet in BSW 243

Solving NMR Structures, Part III:
Use of residual dipolar couplings

Chou article
Chou reading guide
Tjandra et al (optional)
lecture slides (PPT),

see also Teng, p.28-32

None

Special topics: Relaxation and protein
size, TROSY and deuteration

None

Computer lab 4

Incompatible restraints in the linker region of calmodulin

meet in BSW 243

Catch up on Thursday's material

none

Backbone dynamics

lecture notes handout p. D1-D6
Barbato article (PDF)
Barbato reading guide (PDF)

Chemical and conformational exchange

midterm exercise (doc) (PDF)

Midterm due Mar 26