- DNA Nucleases. N.C. Horton. In Protein-Nucleic Acid Interactions: Structural Biology; Carl C. Correll, Ed.; RSC Publishing: Cambridge, United Kingdom, (2008)
- Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA. Segal D.J., Crotty J.W., Bhakta M.S., Barbas C.F. 3rd, and N.C. Horton (2006) J. Mol Biol. 363, 405-21.
- Alteration of Sequence Specificity of the Type II restriction endonuclease HincII through an indirect readout mechanism. Joshi, H.K., Etzkorn, C., Chatwell, L., Bitinaite, J., and N.C. Horton (2006) J Biol Chem. 281, 23852-69.
- DNA induced conformational changes in type II endonucleases; the structure of unliganded HincII. Little, E.J. and N. C. Horton (2006) J. Mol. Biol. 351, 76-88.
- Crystallization and preliminary X-ray crystallographic analysis of Aart, a designed six-finger zinc-finger peptide, bound to DNA. Crotty, J.W., Etzkorn, C., Barbas, III, C.F., Segal, D.J., and N. C. Horton (2005) Acta. Cryst. F61, 573-576.
- Mechanistic insights from the structures of HincII bound to cognate DNA cleaved from addition of Mg2+ and Mn2+. Etzkorn, C., and N.C. Horton (2005) Journal of Molecular Biology 343, 833-849.
- Ca2+ Binding in the active site of HincII: implications for the catalytic mechanism. Etzkorn, C., and N.C. Horton (2004) Biochemistry 43, 13256-13270.
- DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites. N.C. Horton and J.J. Perona (2004) Biochemistry 43, 6841-6857.
- Electrostatic contributions to site specific DNA cleavage by EcoRV endonuclease. N.C. Horton, C. Otey, S. Lusetti, M.D. Sam, J. Kohn, A.M. Martin, V. Ananthnarayan, and J.J. Perona (2002) Biochemistry, 41, 10754-10763.
- Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation. N.C. Horton, L.F. Dorner, and J.J. Perona (2002) Nature Structural Biology, 9, 42-47.
- Catalytic efficiency and sequence selectivity of a restriction endonuclease modulated by a distal manganese ion binding site. M.D. Sam, N.C. Horton, T.A. Nissan, and J.J. Perona (2002) Journal of Molecular Biology 306, 851-861.
- Making the most of metal ions. N.C. Horton and J.J. Perona (2001) Nature Structural Biology, 4, 290-293.
- Mechanism of inhibition of phosphoryl transfer in EcoRV by 3'S phosphorothiolates. N.C. Horton, B.A. Connolly, and J.J. Perona (2000) JACS 122, 3314-3324.
- Crystallographic snapshots along a protein-induced DNA bending pathway. N.C. Horton and J.J. Perona (2000) Proc. Natl. Acad. Sci, USA 97, 5729-5734.
- Crystallization and preliminary diffraction analysis of the HincII restriction endonuclease -DNA complex. N.C. Horton, L.F. Dorner, I. Schildkraut, and J.J. Perona (1999) Acta Cryst. D. 55, 1-3.
- Divalent metal dependence of site-specific DNA binding in EcoRV endonuclease. A.M. Martin, N.C. Horton, S. Lusetti, N.O. Reich, and J.J. Perona (1999) Biochemistry 38, 8430-8439.
- Role of protein-induced bending in the specificity of DNA recognition: Crystal structure of EcoRV endonuclease complexed with d(AAAGAT)+d(ATCTT). N.C. Horton and J.J. Perona (1998) J. Mol. Biol. 277, 779-787.
- Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts. N.C. Horton and J.J. Perona
(1998) J. Biol. Chem. 273, 21721-21729.
- Metal ion mediated substrate-assisted catalysis in type II restriction endonucleases. N.C. Horton, K.J. Newberry, and J.J. Perona (1998) Proc. Natl. Acad. Sci., USA 95, 13489-13494.
- Cation binding to the integrin CD11b I domain and activation model assessment. E.T. Baldwin, R.W. Sarver, G.L. Bryant,Jr. , K.A. Curry, M.B. Fairbanks, B.C. Finzel, R.L. Garlick, R.L. Heinrikson, N.C. Horton, L.C. Kelley, A.M. Mildner, J.B. Moon, J.E. Mott, V.T. Mutchler, C.C. Tomich, K.D. Watenpaugh, and V.H. Wiley (1998) Structure 6, 923-935.
- Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors. N. Horton, M. Lewis, and P. Lu (1997) J. Mol. Biol. 265, 1-7.
- The structure of an RNA/DNA hybrid: a substrate of the ribonuclease activity of HIV-1 reverse transcriptase. N.C. Horton and B.C. Finzel (1996) J. Mol. Biol. 264, 521-533.
- Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. M. Lewis, G. Chang, N.C. Horton, M.A. Kercher, H.C. Pace, M.A. Schumacher, R.G. Brennan, and P. Lu (1996) Science 271, 1201-1332.
- Calculation of the free energy of association for protein complexes. N. Horton and M. Lewis (1996) Protein Science 1, 169-181.
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