Isoe, J., Zamora, J. and Miesfeld, R.L.. (2008) Molecular analysis of the Aedes aegypti carboxypeptidase gene family. Insect. Bioc. Mol. Biol., in revision, PDF file.
Brandon, M.C., Pennington, J.E., Zamora, J., Isoe, J., Schillinger, A-S. and Miesfeld, R.L.. (2008) TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes. Insect. Bioc. Mol. Biol., in revision, PDF file.
Scaraffia, P.Y., Tang, G., Isoe, J., Wysocki, V.H., Wells, M.A. and Miesfeld, R.L. (2008) Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes, Proc. Nat. Acad. Sci., 105:518-523. PDF file.
Yamamoto, M., Watt, C., Schmidt, R., Kuscuoglu, U., Miesfeld, R.L. and Goldhamer, D. (2007) Cloning and characterization of a novel MyoD enhancer-binding factor. Mech. Develop., 124:715-728. PDF file.
Isoe, J., Kunz, S., Manhart, C., Wells, M.A. and Miesfeld, R.L. (2007) Regulated expression of microinjected DNA in adult Aedes aegypti mosquitoes. Insect Mol. Biol., 16:83-92. PDF file.
Wang, J., Cai, Y.. Pen, R., Chauhan, S., Miesfeld, R.L. and Ittmann, M. (2006) Increased Expression of the Metastasis Associated Gene Ehm2 in Prostate Cancer, The Prostate 66:1641-52. PDF file.
Gottwald, E., Herschbach, M., Lahni, B., Miesfeld, R.L., Kunz, S., Raynes, D. and Guerriero, V. (2006). Expression of the cochaperone HspBP1 is not coordinately regulated with Hsp70 expression. Cell Biol. Int., 30:553-558. PDF file.
Chauhan S, Childers, R., Himes, J., Pierce, A., Sykes, S., Pond, K., Kunz, S. and Miesfeld R. (2006) Characterization of the FERM domain protein EHM2 in human cancer cells. In "Adhesion and Cytoskeletal Molecules in Metastasis," Eds., A. Cress and R. Nagle, pp. 91-102, Springer Science. PDF file.
Chauhan, S., Kunz, S., Davis, K., Roberts, J., Martin, G., Demetriou, M., Sroka, T., Cress, A., and Miesfeld, R. (2004) Androgen control of cell proliferation and cytoskeletal reorganization in human fibrosarcoma cells: Role of RhoB signaling. J. Biol. Chem. 279:937-944. PDF file.
Bloom, J.W., Chacko, J., Lohman, M.S., Halonen, M., Martinez, F.D., and Miesfeld, R. (2004) Differential control of eosinophil survival by glucocorticoids, Apoptosis, 9:97-104. PDF File.
Kunz, S., Sandoval, R., Carlsson, P., Carlstedt-Duke, J., Bloom, J. and Miesfeld, R. (2003) Identification of a novel glucocorticoid receptor mutation in budesonide-resistant human bronchial epithelial cells, Mol. Endcrinol., 17:2566-2582. PDF file.
Chauhan, S., Pandey, R., Way, J., Sroka, T., Demetriou, M., Kunz, S., Cress, A., Mount, D., and Miesfeld, R. (2003) Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation, Bioc. Biophys. Res. Com. 310:421-432. PDF file.
Chauhan, S., Leach, C., Kunz, S., Bloom, J. and Miesfeld, R. (2003) Glucocorticoid regulation of human eosinophil gene expression, J. Steroid Bioc. Mol. Biol., 84:441-452, PDF file.
Whitacre, D.C., Chuahan, S., Davis, T., Gordon, D., Cress, A.E., and Miesfeld, R., (2002) Androgen-induction of in vitro prostate cell differentiation, Cell Growth Diff. 13:1-11. PDF file
Whitacre, D.C., Chamberlain, N.L., Karnas, K.J. and Miesfeld, R. (2001) Analysis of glucocorticoid and androgen receptor gene fusions delineates domains required for transcriptional specificity. Endocrine 15:111-118. (PubMed) PDF file.
Miesfeld, R. (2000) Glucocorticoid Action: Biochemistry. In Endocrinology, 4th Edition L. J. DeGroot and J.L. Jameson, eds., W.B.Saunders Co., Publishers, New York, pp. 1647-1654.
Askew, D.J., Kuscuoglu, U., Brunner, T., Green, D.R. and Miesfeld, R. (1999) Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid and Fas-mediated apoptosis. Cell Death Diff. 6:796-804. PDF file.
Adkins, K.K., LeVan, T.D., Miesfeld, R. and Bloom, J.W. (1998) Transcriptional regulation of GM-CSF by IL-1b and glucocorticoids in airway epithelial cells, Lung Cell Mol. Physiol. 19:L372-378. PDF file.
LeVan, T.D., Behr, F.D., Adkins, K.K., Miesfeld, R. and Bloom, J.W. (1997) Glucocorticoid-mediated signaling pathways in a bronchial epithelial cell line, Lung Cell. Mol. Physiol. 16:L838-843.
Dowd, D.R., Ryerse, J.S., MacDonald, P.N., Miesfeld, R.L., Kamradt, M.C. (1997) Crosstalk during Ca2+, cAMP, and glucocorticoid-induced gene expression in lymphocytes. Mol. Cell. Endocrinol.128:29-37.
Chapman, M., Askew, D. Kuscuoglu, U., and Miesfeld, R. (1996) Transcriptional control of steroid-regulated apoptosis in murine thymoma cells, Mol. Endocrin 10:967-978. PDF file.
Miesfeld, R. and J. Bloom (1996) Glucocorticoid receptor structure and function. In Topical glucocorticoids in asthma - mechanism and clinical actions, R. Schleimer, W. Busse and P. O'Byrne, eds., Marcel Dekker Publishers, N.Y.
Chamberlain, N.L., Whitacre, D. and Miesfeld, R. (1996) Delineation of two distinct AF-1 activation functions in the androgen receptor N-terminal domain. J. Biol. Chem.271:26772-26778. PDF file.
Waddell, W.R. and Miesfeld, R. (1995) Adenomatous polyposis coli, protein kinases, protein tyrosine phosphatase: the effect of sulindac. J Surg Oncol. 58:252-256.
Bloom, J. and Miesfeld, R. (1995) Molecular mechanism of glucocorticoid action. In Severe Asthma: pathogenesis and clinical management, S. Szefler and D.Y. Leung, eds. Marcel Dekker, Inc. Publishers, New York, N. Y.
Rundlett, S.E. and Miesfeld, R. (1995) Quantitative differences in androgen and glucocorticoid receptor DNA binding properties contributes to receptor-selective transcriptional regulation, Mol. Cell. Endocrinol. 109:1-10.
Gordon, D.A., Chamberlain, N.L., Flomerfelt, F.A. and Miesfeld, R. (1995) A cell-specific and selective effect on transactivation by the androgen receptor, Exp. Cell Res. 217:368-377.
Chapman, M. Qu, N., Pascoe, S., Chen, W-X, Gordon, D., Apostol, C. and Miesfeld, R. (1995) Isolation of Differentially Expressed Sequence Tags (DESTs) representing transcripts induced by glucocorticoids and androgens in hormone-responsive cells, Mol. Cell. Endocrinol. 108:R1-R7.
Lam, M., Dubyak, G., Chen, L., Nuñez, G., Miesfeld, R. and Distelhorst, C. (1994) Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes, Proc. Natl. Acad. Sci., 91:6569-6573.
Flomerfelt, F. and Miesfeld, R. (1994) Recessive mutations in a common pathway block thymoctye apoptosis induced by multiple signals, J. Cell Biol., 127:1729-1742.
Chamberlain, N., Driver, E. and Miesfeld, R. (1994) The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function, Nuc. Acids Res., 22:3181-3186.
Flomerfelt, F.A., Briehl, M.M., Dowd, D.R., Dieken, E.S. and Miesfeld, R. (1993) Elevated glutathione S-transferase gene expression is an early event during steroid-induced lymphocyte apoptosis, J. Cell. Physiol., 154:573-581.
Rundlett, S. Gordon, D. and Miesfeld, R. (1992) Characterization of a panel of rat prostate epithelial cell lines immortalized in the presence or absence of androgens, Exp. Cell Res. 203:214-221.
Dowd, D.R. and Miesfeld, R. (1992) Evidence that glucocorticoid- and cAMP-induced apoptotic pathways in lymphocytes share distal events. Mol. Cell. Biol. 12:3600-3608.
Dieken, E.S. and Miesfeld, R. (1992) Transcriptional transactivation functions localized to the glucocorticoid receptor N terminus are necessary for steroid induction of lymphocyte apoptosis. Mol. Cell. Biol. 12:589-597.
Dowd, D.R., MacDonald, P.N., Komm, B.S., Haussler, M.R. and Miesfeld, R. (1992) Stable expression of the calbindin-D28K cDNA interferes with the apoptotic pathway in lymphocytes, Mol. Endocrin., 6:1843-1848.
Briehl, M.M. and Miesfeld, R. (1991) Isolation and characterization of transcripts induced by androgen withdrawal and apoptotic cell death in the rat ventral prostate.Mol.Endocrin. 5:1381-1388.
Briehl, M. M., Flomerfelt, F.A., Wu, X-P, and Miesfeld, R. (1990). Transcriptional analyses of steroid-regulated gene networks, Mol. Endocrin. 4:287-294.
Rundlett, S., Wu, X-P., and Miesfeld, R. (1990) Functional characterizations of the androgen receptor confirm that the molecular basis of androgen action is transcriptional regulation. Mol. Endocrin. 4:708-714.
Dieken, E. Meese, E., and Miesfeld, R. (1990) nti glucocorticoid receptor transcripts lack sequences encoding the amino terminal transcriptional modulatory domain. Mol. Cell. Biol. 10:4574-4581.
Roger Miesfeld publications prior to 1990 were as a trainee:
1983 -1987 - Postdoctoral fellow with Keith R. Yamamoto at University of California at San Francisco
1979 - 1983 - Graduate Student with Norman Arnheim formerly at Stony Brook University